一、基本信息
王霞,博士,副教授
电子邮箱:xxwang(at)hubu.edu.cn
研究方向:生物质资源综合利用,木质纤维素生物炼制;微生物代谢工程改造,运动发酵单胞菌抗逆性能和底物代谢性能改善;合成生物学与绿色生物制造
二、教育背景
2011.09–2017.06 华东理工大学,发酵工程,工学博士
2007.09–2013.06 山东科技大学,生物工程,工学学士
三、工作经历
2017.07至今 乐鱼·体育中国官方网站,讲师、副教授
四、科研项目
1. 新蛋白质元件设计智能算法研究,科技部“合成生物学”重点研发计划子课题,2020.11–2025.10,20万元,项目骨干
2. 运动发酵单胞菌纤维小体表面展示实现联合生物加工,农业农村部农村可再生能源开发利用重点实验室开放课题,2019.06–2020.06,4万元,主持
3. 木质纤维素生物炼制过程中抑制物胁迫对半胱氨酸生物合成的影响机制研究,湖北省自然科学基金青年项目,2018.03–2020.12,5万元,主持
4. 运动发酵单胞菌葡萄糖代谢产乳酸与乙醇碳分流机制的研究,国家自然科学基金面上项目,2020.01–2023.12,62万元,参与
五、发表论文(#并列一作,*通讯作者)
1. Yang S*, Franden MA, Wang X, Chou YC, Hu Y, Brown SD, Pienkos PT, Zhang M*. (2020) Transcriptomic profiles of Zymomonas mobilis 8b to furfural acute and long–term stress in both glucose and xylose conditions. Frontiers in Microbiology 11, 13.
2. Yang Q, Yang Y, Tang Y, Wang X, Chen Y, Shen Y, Zhan Y, Gao J, Wu B, He M, Chen S, Yang S*. (2020) Development and characterization of acidic–pH–tolerant mutants of Zymomonas mobilis through adaptation and next–generation sequencing–based genome resequencing and RNA–Seq. Biotechnology for Biofuels 13, 144.
3. Yi X, Gao Q, Zhang L, Wang X, He Y, Hu F, Zhang J, Zou G, Yang S, Zhou Z*, Bao J*. (2019) Heterozygous diploid structure of Amorphotheca resinae ZN1 contributes efficient biodetoxification on solid pretreated corn stover. Biotechnology for Biofuels 12, 126.
4. Wang X#, He Q#, Yang Y#, Wang J, Haning K, Yun Hu Y, Wu B, He M, Zhang Y, Bao J, Contreras L*, Yang S*. (2018) Advances and prospects in metabolic engineering of Zymomonas mobilis. Metabolic Engineering 50:57–73
5. Yang Y, Hu M, Tang Y, Geng B, Qiu M, He Q, Chen S, Wang X*, Yang S*. (2018) Progress and perspective on lignocellulosic hydrolysate inhibitor tolerance improvement in Zymomonas mobilis. Bioresources and Bioprocessing 5, 6.
6. Wang X, Gao Q, Bao J*. (2017) Enhancement of furan aldehydes conversion in Zymomonas mobilis by elevating dehydrogenase activity and cofactor regeneration. Biotechnology for Biofuels 10, 24.
7. Wang X#, Khushk I#, Xiao Y, Gao Q, Bao J*. (2017) Tolerance improvement of Corynebacterium glutamicum on lignocellulose derived inhibitors by adaptive evolution. Applied Microbiology and Biotechnology 102, 377–388.
8. Wang X, Gao Q, Bao J*. (2015) Transcriptional analysis of Amorphotheca resinae ZN1 on biological degradation of furfural and 5–hydroxymethylfurfural derived from lignocellulose pretreatment. Biotechnology for Biofuels 8, 136.